1,5-dihydro-4h-pirazolo [3,4-d] pirimidin-4-onas and 1,5-dihydro-4h-pirazolo [4,3-c] piridin-4-onas as pde1 inhibitors

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专利权人:

H. LUNDBECK A/S

发明人:

KARSTEN JUHL,MIKKEL JESSING,MORTEN LANGGARD,PAULO JORGE VIEIRA VITAL,MAURO MARIGO,JAN KEHLER,LARS KYHN RASMUSSEN

申请号：

NI201800092

公开号：

NI201800092A

申请日:

2018.09.25

申请国别(地区):

NI

年份:

2019

代理人:

摘要：

The present invention provides 1,5-dihydro-4h-pirazolo [3,4-d] pirimidin-4-onas and 1,5-dihydro-4h-pirazolo [4,3-c] piridin-4-omnes (I) as pde1 inhibitors and uses them as drugs, especially for the treatment of neurodegenerative disorders and mental disorders.La presente invención proporciona 1,5-dihidro-4H-pirazolo[3,4-d]pirimidin-4-onas y 1,5-dihidro-4H-pirazolo[4,3-c] piridin-4-onas de fórmula(I) como inhibidores de PDE1 y su uso como un medicamento, en particular para el tratamiento de trastornos neurodegenerativos y trastornos psiquiátricos.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/