Icahn School of Medicine at Mount Sinai;Institute for Advanced Study-Louis Bamberger &； Mrs. Felix Fuld Foundation;ECOLE NORMALE SUPERIEURE;Centre national de la recherche scientifique;Université
发明人:
Benjamin D. Greenbaum,Nina Bhardwaj,Arnold Levine,Remi Monasson,Simona Cocco
申请号：
US16786709
公开号：
US20200268786A1
申请日:
2020.02.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a composition comprising an isolated, single stranded RNA molecule having a nucleotide sequence comprising 20 or more bases and a pattern of CpG dinucleotides defined by a strength of statistical bias greater than or equal to zero, and a pharmaceutically acceptable carrier suitable for injection. The present invention also relates to a kit comprising a cancer vaccine and the composition of the present invention as an adjuvant to the cancer vaccine. The present invention further relates to a method of treating a subject for a tumor and a method of stimulating an immune response.
