Mi-La CHO,Dong-Yun SHIN,Min-Jung PARK,Seon-Yeong LEE,Eun Ji YANG,Eun Kyung KIM,Hye-Jin SON,Eun-Jung LEE,Jae-Kyung KIM,Sung-Hee LEE
申请号：
US14913082
公开号：
US20160193180A1
申请日:
2014.08.22
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The daurinol compound according to the present invention exhibits excellent therapeutic effects on arthritis and inflammatory bowel diseases by having an excellent activity in inhibiting the generation of IL-17 and TNF-α, which are inflammatory cytokines causing inflammation, and can alleviate transplant rejection by inhibiting the proliferation of alloreactive T cells and increasing regulatory T cells therefore, the daurinol compound according to the present invention can be used as a pharmaceutical composition capable of treating and preventing immune diseases. In addition, being a natural substance derived from the Mongolian medicinal plant Haplophyllum dauricum or Haplophyllum cappadocicum, the daurinol compound according to the present invention does not cause cytotoxicity and thus may be used as a composition for a functional health food capable of preventing and remedying immune diseases.
