DEhJV Vajpul (US),ДЭЙВ Вайпул (US),FALOTIKO Robert (US),ФАЛОТИКО Роберт (US),LI Chehn'sjueh (US),ЛИ Чэньсюэ (US),NGUJEN Taj M. (US),НГУЙЕН Тай М. (US),PARKER Teodor L. (US),ПАРКЕР Теодор Л. (US),ChZhA,DEHJV VAJPUL,ДЭЙВ Вайпул,FALOTIKO ROBERT,ФАЛОТИКО Роберт,LI CHEHNSJUEH,ЛИ Чэньсюэ,NGUJEN TAJ M.,НГУЙЕН Тай М.,PARKER TEODOR L.,ПАРКЕР Теодор Л.,CHZHAO DZHONATON Z.,ЧЖАО Джонатон З.
申请号:
RU2009146584/14
公开号:
RU0002522390C2
申请日:
2009.12.15
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
FIELD: medicine.SUBSTANCE: group of inventions relates to medicine. An implanted medical device for delivery of a number of medications to a place of intervention in accordance with the first version contains in fact a cylindrical intraluminal framework, a primer layer, the first and second coatings and, at least, one therapeutic preparation. The cylindrical intraluminal framework is expandable from the first diameter for delivery into a vessel to the second diameter for the vessel expansion. The intraluminal framework has a luminal surface and an abluminal surface. The distance between the luminal surface and the abluminal surface specifies a thickness of the intraluminal framework wall. The intraluminal framework also contains a multitude of holes, extending from the luminal to abluminal surface. The primer layer includes a multitude of layers and covers the luminal surface, the abluminal surface and surfaces of the multitude of holes. The first coating contains a material, which has the first electric charge, and is fixed to the primer layer. The second coating contains a material, which has the second electric charge and is fixed to the first coating only in the multitude of holes. The second electric charge is opposite to the first electric charge. The therapeutic preparation is placed in, at least, one of the multitude of holes. The second coating is made in the form of an intermediate layer between the first coating and, at least, one therapeutic preparation. The implanted medical device in accordance with the second version contains a cylindrical intraluminal framework, a layer of first coating, a layer of second coating and, at least, one therapeutic preparation. The cylindrical intraluminal framework is expandable from the first diameter for delivery into a vessel to the second diameter for the vessel expansion and has a luminal surface and an abluminal surface. The distance between the luminal surface and the abluminal surface specifies a thickness of the