This disclosure relates to dosage regimens for targeted TGF-β inhibition with a bi-functional fusion protein for use in a method of treating cancer or inhibiting tumor growth in treatment naïve patients.本發明係關於利用雙功能性融合蛋白進行標靶性TGF-β抑制之給藥方案,其係用於未曾接受過治療之患者中治療癌症或抑制腫瘤生長之方法中。