Pharmaceutical combinations comprising a component (a) corresponding to compounds derived from difenilurea Omega carboxiaril - substituted,(b) compounds derived from N - (2 - arilamino arilsulfonamida) and (c) are one or more additional Pharmaceutical agents and their use in the treatment of cancer
The present invention relates to: combinations of: component A: one or more omega-carboxyaryl-substituted diphenyl urea compounds of general formula (I), or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof； component B: one or more N-(2-arylamino)aryl sulfonamide compounds of general formula (II), or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof； and, optionally, component C: one or more further pharmaceutical agents； in which optionally some or all of the components are in the form of a pharmaceutical formulation which is ready for use to be administered simultaneously, concurrently, separately or sequentially. dependently of one another by the oral, intravenous, topical, local installations, intraperitoneal or nasal route； use of such combinations for the preparation of a medicament for the treatment or prophylaxis of a cancer； and a kit comprising such a combination.COMBINACIONES QUE COMPRENDEN UN COMPONENTE A(4-[4-({[4-CLORO -3-(TRIFLIOROMETIL)FENIL]CARBAMOIL}AMINO)-3-FLUOROFENOXI]-N-METILPIRIDIN -2CARBOXAMIDA),Y UN COMPONENTE B ((S)-N-(3,4-DIFLUORO-2-(2-FLUORO -4-YODOFENILAMINO)-6METOXIFENIL)-1-(2,3DIHIDROXIPROPIL)CICLOPROPAN-1-SULFONAMIDA)；USO PARA TRATAR EL CÁNCER, Y KIT FARMACÁUTICO.
