NOVEL PYRROLES HAVING HYPOLIPIDEMIC HIPOCHOLESTEREMIC ACTIVITIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINE
The present invention relates to novel substituted pyrrole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel substituted pyrrole compounds of the general formula (I), their analogs, their derivatives, their polymorphs, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and their pharmaceutical compositions containing them. This invention also relates to the process for preparing such compounds, a composition containing such a compound and the use of such a compound and composition in medicine.Sadašnji izum se odnosi na nove supstituirane spojeve pirola, njihove derivate, njihove analoge, njihove stereoizomere, njihove polimorfe, njihove farmaceutski prihvatljive soli, njihove farmaceutski prihvatljive solvate i farmaceutski prihvatljive pripravke koji ih sadržavaju. Ovaj izum se posebno odnosi na nove supstituirane spojeve pirola općenite formule (I), njihove derivate, njihove analoge, njihove stereoizomere, njihove polimorfe, njihove farmaceutski prihvatljive soli, njihove farmaceutski prihvatljive solvate i farmaceutski prihvatljive pripravke koji ih sadržavaju. Izum se također odnosi na postupak za pripravu takvih spojeva, pripravka koji sadržava takav spoj i uporabu takvog spoja i pripravka u medicini. Spojevi snižavaju razine triglicerida u krvi i mogu biti korisni u tretiranju debljine, hiperlipidemije, hiperkolesteremije, sindroma X i dijabetesa.