Chawdry, Suliman,Duggirala, Srinivas S.,Gupta, Rajan
申请号：
AU2007269733
公开号：
AU2007269733B2
申请日:
2007.06.29
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Immediate-release formulations for oral administration of a thrombin receptorantagonist are provided. Certain formulations of higher API loading demonstratesufficient moisture uptake after storage at stressed conditions to retard dissolution.The formulations of the present invention incorporate either lower API loadingor elevated disintegrant-to-API ratios, found necessary to achieve disintegrationrates required for immediate-release performance.
