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Biomolecule complexes as contrast agents in Positron Emission Tomography (PET) based methods for the assessment of organ function
专利权人:
发明人:
申请号:
EP11005294.1
公开号:
EP2428231A2
申请日:
2009.12.10
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to complexes comprising one or more markers and one or more biomolecules for use as a contrast agent in positron emission tomography based imaging. The complexes according to the present invention preferably accumulate in a target compartment, such as the kidney. The present invention further relates to methods for generating the complexes and methods for using the complexes such as for evaluation of different aspects of kidney functionality e.g. for calculation of total and/or regional glomerular filtration rate in the kidney without the need for sampling blood or urine.
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