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Magnetic resonance imaging (MRI) based quantitative kidney perfusion analysis
专利权人:
Case Western Reserve University
发明人:
Vikas Gulani,Katherine Wright,Nicole Seiberlich,Mark Griswold
申请号:
US14084678
公开号:
US10147314B2
申请日:
2013.11.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Example apparatus and methods provide improved spatial and temporal resolution over conventional magnetic resonance renography (MRR). Example apparatus and methods reconstruct under-sampled three-dimensional (3D) data associated with nuclear magnetic resonance (NMR) signals acquired from a kidney. The data is reconstructed using a 3D through-time non-Cartesian generalized auto-calibrating partially parallel acquisitions (GRAPPA) approach. Example apparatus and methods produce a quantized value for a contrast agent concentration in the kidney from a signal intensity in the data based, at least in part, on a two compartment model of the kidney. The two compartment model includes a plasma compartment and a tubular compartment. The quantized value describes a perfusion parameter for the kidney or a filtration parameter for the kidney. Greater precision is achieved for estimates of the perfusion parameter or filtration parameter as a result of the quantization performed on data acquired with greater spatial resolution and temporal resolution.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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