HORMONA DE CRESCIMENTO MODIFICADA COM POLIETILENOGLICOL DE CADEIA DUPLA, MÉTODO DE PREPARAÇÃO E APLICAÇÃO DESTE

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专利权人:

BIOSTEED GENE EXPRESSION TECH. CO.; LTD.

发明人:

WEIDONG ZHOU,LI SUN,XIAOJIN LIAO,LINZHONG ZHANG,QINGSONG LU,SHIYE SHEN,LISHAN YANG,DEFANG ZHANG,HUIHUANG LIN,PING ZHANG

申请号：

PT08733888

公开号：

PT2272875E

申请日:

2008.04.03

申请国别(地区):

PT

年份:

2014

代理人:

摘要：

The growth hormone with high biological activity modified by the double-stranded polyethylene glycol at a single site and the preparation method thereof are provided. The PEGylated growth hormone has a higher biological activity and a longer half-life than the unmodified growth hormone. The composition comprising the PEGylated growth hormone is useful in the treatment of the growth or development disorder such as growth hormone deficiency, Turner syndrome etc..

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