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OLIGOMER-SPECIFIC AMYLOID BETA EPITOPE AND ANTIBODIES
专利权人:
THE UNIVERSITY OF BRITISH COLUMBIA
发明人:
CASHMAN NEIL R
申请号:
ZA201206916
公开号:
ZA201206916B
申请日:
2012.09.14
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
An isolated antibody that specifically binds to a cyclic peptide comprising the conformational epitope which has at least the amino acid sequences GSNK or SNKG, wherein the K (lysine) is solvent-exposed and wherein the antibody can specifically bind to amyloid beta is described. Methods of treating and preventing Alzheimers disease, as well as methods to produce the antibody, are also described.
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