MARTINEZ BOTELLA, Gabriel,SALITURO, Francesco G.,ROBICHAUD, Albert Jean,HARRISON, Boyd L.
申请号:
AU2020202892
公开号:
AU2020202892A1
申请日:
2020.04.30
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020202892A120200521.pdf#####ABSTRACT Described herein are neuroactive steroids of the Formula (I): A R4 R3 a H R 2 R1 HO' R 5 R 7a R7b or a pharmaceutically acceptable salt thereof; wherein ---- , A, R, R2, R3a, R 4a, R4b, R, R7 7a, and R 7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.