Martinez Botella, Gabriel,Salituro, Francesco G.,Robichaud, Albert Jean,Harrison, Boyd L.
申请号:
AU2020207810
公开号:
AU2020207810A1
申请日:
2020.07.21
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020207810A120200806.pdf#####Abstract Described herein are neuroactive steroids of the Formula (I): R2 b A R 2a O H H R": HO~ R3 (I or a pharmaceutically acceptable salt thereof; wherein , R', R2 a, R2 , Rand A are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.