Sebastien Daniel MORISSEAU,Geraldine TEPPAZ,Yannick Laurent Joseph JACQUES,Bruno Gilbert Marc ROBERT,Guy Luc Michel DE MARTYNOFF,David BECHARD
申请号:
US16012174
公开号:
US20180312560A1
申请日:
2018.06.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and (ii) a polypeptide comprising the amino acid sequence of the sushi domain of the interleukin 15R alpha (IL-15Rα) or derivatives thereof and uses thereof