An ECG lead system for use with a plurality of unique diverse ECG floor monitors for when a patient is substantially immobile and/or a plurality of unique diverse ECG telemetry monitors, is provided. The ECG lead system includes a plurality of unique adapters, wherein each adapter includes an input receptacle configured for selective electrical connection with a device connector of an ECG lead set assembly and at least one unique monitor plug electrically connected to the input receptacle. Each monitor plug is configured to selectively electrically connect to a corresponding receptacle of a respective unique diverse ECG floor monitor or unique diverse ECG telemetry monitor.