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INDOLE-3-CARBOXAMIDES CYCLIQUES, LEUR PREPARATION ET LEUR UTILISATION COMME PRODUITS PHARMACEUTIQUES
专利权人:
SANOFI
发明人:
申请号:
EP09706006.5
公开号:
EP2247575B1
申请日:
2009.01.17
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to cyclic indole-3-carboxamides of the formula I, wherein A, R, R10, R20, R30, R40, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.
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