Bodo Scheiper,Gary Mccort,Hans Ulrich Stilz,Henning Steinhagen
申请号：
BRPI0906433
公开号：
BRPI0906433A2
申请日:
2009.01.17
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention relates to cyclic indole-3-carboxamides of the formula I, wherein A, R, R10, R20, R30, R40, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.
