SHIVANAND LAD,WILLIAM C. MOBLEY,KAROLY NIKOLICH,THOMAS SAUL
申请号：
US16548554
公开号：
US20200046954A1
申请日:
2019.08.22
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
