William C. Mobley;Karoly Nikolich;Shivanand Lad;Thomas Saul
发明人:
Shivanand Lad,William C. Mobley,Karoly Nikolich,Thomas Saul
申请号:
US12444581
公开号:
US08435204B2
申请日:
2007.10.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. A multilumen flow path allows exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.