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HEAVY CHAIN ANTIBODIES BINDING TO ECTOENZYMES
专利权人:
TENEOBIO; INC.
发明人:
Starlynn Clarke,Kevin Dang,Shelley Force Aldred,Nathan Trinklein,Wim van Schooten
申请号:
US16646970
公开号:
US20200207867A1
申请日:
2018.09.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Human heavy chain antibodies, such as UniAbs™;, binding to ectoenzymes are provided along with combinations of such heavy chain antibodies and multi-specific heavy chain antibodies, targeting non-overlapping epitopes on ectoenzymes, including synergistic combinations. Methods of making such antibodies, compositions including pharmaceutical compositions comprising such antibodies, and methods directed to the treatment of disease or conditions associated with the expression of ectoenzymes are also included.
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