An automated device and method for obtaining a tissue biopsy and the delivery of a material to provide hemostatis, therapeutic agents or marker material is described that can be used in conjunction with a cutting needle biopsy device. The device has an outer casing, a power source, a drive mechanism, an application chamber through which the biopsy mechanism, typically a cutting need device, passes through and an application channel. The cutting biopsy mechanism has a mechanical or electromechanical mechanism to rapidly fire a stylet with a biopsy trough into the intended tissue and then rapidly propel a biopsy cannula over the stylet to sever and retain tissue that has protruded into the biopsy trough. At least one application channel is formed by a tube centrically slipped over the biopsy cannula wall. To enable the collection of tissue specimens, the distal segment of the application channel forms a close fitting and concentric sheath around the biopsy cannula. The biopsy cannula wall projects out of the tube with its acute-angularly designed cutting edge and the tube end encloses an obtuse angle with the biopsy cannula. The proximal end of the application channel has a larger diameter than the distal end allowing for unobstructed flow of the application material past the biopsy cannula wall upon retraction of the biopsy cannula from the distal segment of the application channel. The drive mechanism contains holders for placement of the application chamber and the biopsy mechanism and a method to manipulate the proper sequence and movement of the two.La présente invention concerne un dispositif et un procédé automatisé dobtention dune biopsie de tissu et la livraison dune matière pour fournir une hémostase, des agents thérapeutiques ou un matériau marqueur qui peuvent être utilisés en conjonction avec un dispositif de biopsie à aiguille de découpe. Ce dispositif comprend un boîtier externe, une source d’alimentation, un mécanisme d’entraînement, une chambre d’appl