ALCALOIDES STEROIDIENS ET LEURS UTILISATIONS EN TANT QU'AGENTS ANTIMICROBIENS CONTRE LES MICRO-ORGANISMES A DEFAUT DE TRANSPORT D'ELECTRONS ET EN TANT QU'EXHAUSTEURS D'AGENTS MICROBIENS CONTRE DES BACTERIES PATHOGENES
BOUARAB, KAMAL,BOULANGER, SIMON,CHAGNON, FELIX,GUAY, ISABELLE,MALOUIN, FRANCOIS,MARSAULT, ERIC,MITCHELL, GABRIEL
申请号：
CA2828047
公开号：
CA2828047A1
申请日:
2012.02.15
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention includes novel compounds based on the tomatidine skeleton as well as composition comprising these compounds alone and in combination with known compounds, which exhibit antimicrobial activity against extracellular or intracellular electron transport-deficient microbes and/or increase the antimicrobial activity of aminoglycoside antibiotics against their targets, and which are useful as antibacterial agents for treatment or prophylaxis of monomicrobiotic or polymicrobic bacterial infections or for the reduction of antibiotic resistance development in animals or in humans, or for use as antiseptics or agents for sterilization or disinfection.
