VIRUS MUTANTS, METHODE DE PREPARATION ET UTILISATION ASSOCIEE

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专利权人:

PEKING UNIVERSITY

发明人:

ZHOU, DEMIN,SI, LONGLONG,ZHOU, XUEYING,ZHANG, ZIWEI,XU, HUAN,TIAN, ZHENYU,ZHANG, CHUANLING,XIAO, SULONG,XIA, QING,ZHANG, LIHE

申请号：

CA3010015

公开号：

CA3010015A1

申请日:

2016.08.02

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention provides a mutant virus, preferably an influenza virus, from a human or another animal, and a preparation method for the mutant virus. The method comprises of introducing a UAG codon upstream of an endogenous stop codon of one or more genes in a viral genome. The invention further provides applications of the mutant virus as an attenuated live vaccine or as a replicable and controllable safe virus model.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/