Mutant virus, preparation method therefor and application thereof

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专利权人:

Peking University

发明人:

Zhou, Demin,Si, Longlong,Zhou, Xueying,Zhang, Ziwei,Xu, Huan,Tian, Zhenyu,Zhang, Chuanling,Xiao, Sulong,Xia, Qing,Zhang, Lihe

申请号：

AU2016383201

公开号：

AU2016383201A1

申请日:

2016.08.02

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present invention provides a mutant virus, preferably an influenza virus, from a human or another animal, and a preparation method for the mutant virus. The method comprises of introducing a UAG codon upstream of an endogenous stop codon of one or more genes in a viral genome. The invention further provides applications of the mutant virus as an attenuated live vaccine or as a replicable and controllable safe virus model.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/