Management systems and methods for managing physiology data measurement are provided. First, physiology data input is received. Next, a measurement schedule is obtained according to the physiology data input, wherein the measurement schedule includes a measurement frequency and at least one measurement time point corresponding thereto. Thereafter, at the measurement time point, physiology data measurement is performed to obtain a measured value. The measurement frequency and/or the measurement time point of the measurement schedule is dynamically updated based on the measured value and a predefined abnormality determination criterion and subsequent measurements are to be performed with the updated measurement frequency and/or the measurement time point.