DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-1H-INDOL-3-YL]-METHANONES农业专利-农业学术服务平台

发明人:: CHOI-SLEDESKI, YONG-MI,GARDNER, CHARLES, J.,LIANG, GUYAN,POLI, GREGORY, B.,SHUM, PATRICK, WAI-KWOK,STOKLOSA, GREGORY, T.,ZHAO, ZHICHENG

摘要：: THE PRESENT INVENTION EXTENDS TO THE COMPOUND OF FORMULA I: OR A PRODRUG, PHARMACEUTICALLY ACCEPTABLE SALT, OR SOLVATE OF SAID COMPOUND. FURTHERMORE, THE PRESENT INVENTION IS DIRECTED TO A PHARMACEUTICAL COMPOSITION COMPRISING A PHARMACEUTICALLY EFFECTIVE AMOUNT OF THE COMPOUND OF FORMULA I, AND A PHARMACEUTICALLY ACCEPTABLE CARRIER. FURTHERMORE, THE PRESENT INVENTION IS DIRECTED TO THE USE OF A COMPOUND OF FORMULA I AS AN INHIBITOR OF TRYPTASE, COMPRISING INTRODUCING THE COMPOUND INTO A COMPOSITION COMPRISING TRYPTASE. IN ADDITION, THE PRESENT INVENTION IS DIRECTED TO THE USE OF A COMPOUND OF FORMULA I FOR TREATING A PATIENT SUFFERING FROM, OR SUBJECT TO, A PHYSIOLOGICAL CONDITION IN NEED OF AMELIORATION OF AN INHIBITOR OF TRYPTASE COMPRISING ADMINISTERING TO THE PATIENT A THERAPEUTICALLY EFFECTIVE AMOUNT OF THE COMPOUND OF CLAIM 1. THE PRESENT INVENTION IS DIRECTED ALSO TO THE PREPARATION OF A COMPOUND OF FORMULA I.