ALEXANDRE GEISSLER,SOULA GÉRARD,SOULA OLIVIER,TONNAR JEFF
申请号:
BR112014002986
公开号:
BR112014002986A2
申请日:
2012.08.09
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
A composition in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, includes at least a basal insulin, the isoelectric point pI of which is between 5.8 and 8.5 and a dextran substituted by radicals carrying carboxylate charges and hydrophobic radicals. Single-dose formulations at a pH of between 7 and 7.8 includes a basal insulin whose isoelectric point is between 5.8 and 8.5 and a prandial insulin.