Devices, systems, and methods for tissue measurement are provided. In general, the devices, systems, and methods can allow a size of a target tissue, e.g., a wound, of a patient to be determined by tracing a perimeter of the target tissue using a handheld device. Examples of the size of the target tissue include a length of a perimeter of the target tissue, a surface area of the target tissue, a depth of the target tissue, and a volume of the target tissue.