HEUSSER, CHRISTOPH,NEUGEBAUER, JULIA,SCHAADT, EVELINE,URLINGER, STEFANIE,WOISETSCHLAEGER, MAXIMILIAN
申请号:
PL09797499
公开号:
PL2315780T3
申请日:
2009.07.15
申请国别(地区):
PL
年份:
2016
代理人:
摘要:
The present invention relates to antibodies that specifically bind to the BAFF receptor (BAFFR). The invention more specifically relates to specific antibodies that are BAFFR antagonists with in vivo B cell depleting activity and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by killing or depleting B cells, such as systemic lupus erythematosus or rheumatoid arthritis or other autoimmune diseases or lymphomas, leukemias and myelomas.