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antibodies and their methods of use
专利权人:
AGENUS INC.;LUDWIG INSTITUTE FOR CANCER RESEARCH LTD;MEMORIAL SLOAN KETTERING CANCER CENTER
发明人:
CORNELIA ANNE MUNDT,DAVID ADAM SAVITSKY,DAVID SCHAER,GERD RITTER,IGOR PROSCURSHIM,JEAN-MARIE CUILLEROT,JEDD DAVID WOLCHOK,MARC VAN DIJK,MARK ARTHUR FINDEIS,NICHOLAS STUART WILSON,OLGA SHEBANOVA,RIKKE
申请号:
BR112019011582
公开号:
BR112019011582A2
申请日:
2017.12.07
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
antibodies that specifically bind to ctla-4 and / or pd-1 are provided and antagonize the function of ctla-4 and / or pd-1. Also provided are pharmaceutical compositions and kits which include such antibodies, nucleic acids encoding such antibodies, expression vectors and host cells for the production of such antibodies and methods of treating patients using such antibodies, alone or in combination.são fornecidos anticorpos que se ligam especificamente ao ctla-4 e/ou pd-1 e antagonizam a função do ctla-4 e/ou pd-1. são igualmente fornecidos composições e kits farmacêuticos que incluem tais anticorpos, ácidos nucleicos que codificam tais anticorpos, vetores de expressão e células hospedeiras para a produção de tais anticorpos e métodos de tratamento de pacientes que utilizam tais anticorpos, isolados ou combinados.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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