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含有聯苯乙酸之經皮吸收製劑
专利权人:
LTD.;TEIKOKU SEIYAKU CO.
发明人:
KATAYAMA, AKIKO,片山明子,INOO, KATSUYUKI,猪尾胜幸,豬尾勝幸
申请号:
TW099143614
公开号:
TWI491690B
申请日:
2010.12.14
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
The present invention provides a dermal absorption agent comprising felbinac which substantially contains no solubilizer of felbinac in the final formulation and shows high release ability of felbinac; a patch combining lidocalin and felbinac wherein it does not decrease the release ability of lidocalin and shows release ability of felbinac. A dermal patch comprising felbinac is characterized by comprising felbinac as active ingredient and lidocalin or pharmaceutically acceptable salt thereof as sorbefacient; especially, in the dermal patch comprising felbinac, a content of felbinac is 0.1~10 wt% relative to a total weight of medicine containing-paste, and a content of lidocalin or pharmaceutically acceptable salt thereof is 0.01~20 wt% relative to a total weight of medicine containing-paste.本發明提供一種含有聯苯乙酸之經皮吸收製劑,在最終製劑中實質上不含有聯苯乙酸的助溶劑,能顯示聯苯乙酸的高度釋放性,於摻配有木卡因與聯苯乙酸的貼劑中,不損及木卡因的釋放性而能顯示聯苯乙酸的釋放性。一種含有聯苯乙酸之經皮吸收貼劑,其特徵為含有聯苯乙酸作為有效成分,並含有木卡因或其藥學上可被容許之鹽作為吸收促進劑,特別是聯苯乙酸的含量相對於含有藥物的膏體總重量為0.1至10重量%,木卡因或其藥學上可被容許的鹽的含量相對於含有藥物的膏體總重量為0.01至20重量%。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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