The Board of Trustees of the Leland Stanford Junior University;U.S. Government as Represented By the Department of Veterans Affairs
发明人:
Anton Wyss-Coray,Joseph M. Castellano
申请号:
US15736583
公开号:
US20180353578A1
申请日:
2016.06.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.