A deep vein thrombosis prevention garment includes an S-shaped body having a central panel, a left and a right side panels both formed with a number of offset and opposing attachment straps having an integral fastener. The central panel is formed to have a single air chamber receiving air from a pump through a flexible air supply tube. The central panel, left side panel and right side panel are formed from a single material which does not require a skin-safe liner or other combination of materials. A single-chamber bladder is attached to the central panel. A cover panel, sized to cover the inside surface of the central panel, covers the single-chamber bladder and is attached along its perimeter to the central panel. The cover panel and the body are made from the same material which can be placed against a patients skin.
