A pet sanitation device provides a litter-containing basket in a housing, with a spinner/agitator in the basket. After a pet uses the device, the housing and basket are filled with water to dissolve waste in the litter, and the spinner/agitator is caused to spin at a first, relatively slower speed within the basket to help break-up the waste. The basket is then caused to spin at a second, relatively faster speed in the housing, and this second spinning motion produces centrifugal forces that force the wastewater outward from the basket and into the space between the basket and the housing. The wastewater is drained from the housing, leaving the device ready for a subsequent use.