LICHENSTEIN, HENRI,BEEHARRY, NEIL,LANDRETTE, SEAN,GAYLE, SOPHIA,GROTZKE, JEFF,HERNANDEZ, MARYLENS,YOUNG, PETER R.,ROTHBERG, JONATHAN M.
申请号:
CA3076915
公开号:
CA3076915A1
申请日:
2018.09.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The disclosure provides methods for treating cancer, including but not limited to, hematopoietic and lung cancers, using the HSP90 inhibitor, MPC-0767, as monotherapy and in combination therapy with additional active agents, including but not limited to, inhibitors of Bcl -2, EZH2 inhibitors, Ras/Raf/MEK/ERK pathway inhibitors, checkpoint inhibitors, DNMT inhibitors, ATO and chemotherapeutic agents. The disclosure also provides related compositions and methods of use.