ANTICORPS SELECTIFS DES CELLULES PRESENTATRICES DES RECEPTEURS DE EGF A HAUTE DENSITE

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专利权人:

YM BIOSCIENCES INC.;NATIONAL RESEARCH COUNCIL OF CANADA

发明人:

TIKHOMIROV, ILIA ALEXANDRE,JARAMILLO, MARIA,O'CONNOR-MCCOURT, MAUREEN D.,SULEA, TRAIAN,GILBERT, RENALD,GAILLET, BRUNO,BAARDSNES, JASON,BANVILLE, MYRIAM,GROTHE, SUZANNE

申请号：

CA2825255

公开号：

CA2825255A1

申请日:

2012.01.20

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Herein described are antibodies to epidermal growth factor receptor (EGFR) having an EGFR binding affinity that is sufficient to kill disease cells presenting EGFR at high density, but is insufficient for binding to normal cells. A therapeutic effect is thus achieved while avoiding adverse events that result from unintended binding to normal cells.

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