DUKSUNG WOMENS UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;덕성여자대학교 산학협력단;DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
KIM, GUN HEE,김건희,CHANG, KYUNG MI,장경미
申请号：
KR1020110137063
公开号：
KR1020130069982A
申请日:
2011.12.19
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: An essential oil of Zanthoxyli fructus is provided to enhance ALP activity, collagen synthesis, calcium accumulation, to promote bone formation, and to be used as a pharmacological formulation for treating osteoporosis. CONSTITUTION: A pharmaceutical composition for preventing or treating osteoporosis contains essential oil of Zanthoxyli fructus as an active ingredient. The essential oil is prepared by steam distillation, hot water distillation, oil adsorption, solvent extraction, supercritical fluid extraction, or pressing. The essential oil contains one or more kinds of compounds selected from the group consisting of beta-phellandren, citronellal, geranyl acetate, beta-myrcene, citronellyl acetate, acetate, citronellol, krypton, linalool, cuminol, nonanoic acid, alpha-terpinolene, geranial, and piperitone. Health food for treating osteoporosis contains the essential oil of Zanthoxyli fructus as an active ingredient. [Reference numerals] (AA) Cell growth(%)； (BB) Zanthoxyli fructus essential oil(ug/mL)본 발명은 골다공증 예방 또는 치료용 조성물에 관한 것으로서, 보다 상세하게는 산초의 정유를 유효성분으로 함유하는 골다공증 예방 또는 치료용 약학적 조성물 및 건강식품에 관한 것이다. 상기 산초의 정유는 조골세포의 ALP 활성, 콜라겐 합성 및 칼슘 축적을 증가시켜 골형성을 촉진시킴으로써 골다공증을 치료하기 위한 약리학적 제제로 유용하게 사용될 수 있다.
