The present invention concerns a preparation method of adhesive patch that can be easily affixed to skin and a device thereof, comprising step 1 of forming an adhesive layer (14) on a supporting body (12), step 2 of connecting a tab-forming sheet (18) with a release sheet (16), step 3 of forming a weakened section (20) on the release sheet (16) and the tab-forming sheet (18), and step 4 of adhering the release sheet (16) connected to the tab-forming sheet (18) from step 3 in a removable manner to the adhesive layer (14) on the supporting body (12) from step 1.