ANDERSSON, SVEN-BOERJE,BERGENGREN, GUNNAR,BOSSON, BENGT,HUGERTH, ANDREAS,NICKLASSON, FREDRIK,OLSSON, ROLAND
申请号：
EP08741851
公开号：
EP2152313A4
申请日:
2008.04.21
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least one amino acid, preferably at least one endogenous amino acid. Also contemplated is a method for the oral delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as methods for manufacturing the oral formulation, the use of said oral formulation for obtaining transmucosal uptake of nicotine in the oral cavity of a subject, and use of nicotine for the production of an oral formulation as per above for the treatment of a disease selected from the group consisting of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerous colitis and post-smoking-cessation weight control.
