For manufacturing positively charged liposome vesicle lipophilic molecules as carrier. A kind of hydrogenated phospholipid of mixture, cationic excipient and lipophilic molecules dissolution are in a solvent to form composition. Composition is dried and removed into solvent. Dry compositions are hydrated and form liposome vesicle and optionally liposome vesicle homogenizes with the smaller vesicle of formation. Vesica can be used for delivery lipophilic molecule, for example, but be not limited to, lutern and zeaxanthin, until ocular tissue iontherapy.