Administration of anti-CD3 antibodies in the treatment of autoimmune diseases

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专利权人:

GLAXO GROUP LIMITED

发明人:

VAICKUS, LOUIS,PONATH, PAUL,ROSENZWEIG, MICHAEL

申请号：

AU2012201443

公开号：

AU2012201443A1

申请日:

2012.03.09

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

ADMINISTRATION OF ANTI-CD3 ANTIBODIES IN THE TREATMENT OF AUTOIMMUNE DISEASES Abstract A method of treating an autoimmune disease, such as, diabetes or psoriasis, by administering an anti-CD3 antibody, or anti-CD3 antibody fragment. The anti-CD3 antibody, or anti-CD3 antibody fragment, is administered over a course of treatment wherein, during the course of treatment, the anti-CD3 antibody, or anti-CD3 antibody fragment is administered in a total amount which does not exceed 300pg/kg when administered intravenously or, when administered other than intravenously, is administered in a total amount that does not exceed a total amount bioequivalent to 300ptg/kg of intravenous administration thereof.

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