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Methods and apparatus for neuromodulation
专利权人:
NuVu LLC;Massachusetts Institute of Technology
发明人:
Nir Grossman,David Wang,Edward Boyden
申请号:
US15215597
公开号:
US10448883B2
申请日:
2016.07.21
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A neuromodulator accurately measures—;in real time and over a range of frequencies—;the instantaneous phase and amplitude of a natural signal. For example, the natural signal may be an electrical signal produced by neural tissue, or a motion such as a muscle tremor. The neuromodulator generates signals that are precisely timed relative to the phase of the natural signal. For example, the neuromodulator may generate an exogenous signal that is phase-locked with the natural signal. Or, for example, the neuromodulator may generate an exogenous signal that comprises short bursts which occur only during a narrow phase range of each period of an oscillating natural signal. The neuromodulator corrects distortions due to Gibbs phenomenon. In some cases, the neuromodulator does so by applying a causal filter to a discrete Fourier transform in the frequency domain, prior to taking an inverse discrete Fourier transform.
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