PROBLEM TO BE SOLVED: To provide a bone regeneration material which is excellent in bondability with surrounding tissues because of its granular shape, and has good bone reproducing ability even if the granule is broken.SOLUTION: The shell granule or the aggregate thereof is formed of a hard body which contains a hydraulic powder composition in its inside and has a shell obtained by hydration reaction of the powdery composition.COPYRIGHT: (C)2012,JPO&INPIT【課題】顆粒の形状を有することによる周囲組織との結合性に優れ、かつ顆粒が破壊された場合でも良好な骨再生能を保持する骨再生用材料を提供する。【解決手段】内部に水硬性粉体状組成物を含有し、外殻が前記粉体状組成物を水和反応させて得られる硬化体で形成されてなるシェル状顆粒又はその凝集体。【選択図】なし