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Oral glucagon-like peptide conjugates for metabolic diseases
专利权人:
Kenneth D. James
发明人:
Kenneth D. James
申请号:
US12090306
公开号:
US08759290B2
申请日:
2006.10.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to the field of metabolic compound conjugates, methods of forming said conjugates and uses of these conjugates in the treatment of diabetes and conditions related to this condition. The metabolic compound conjugates of this invention include a metabolic peptide having a glucagon-like peptide (GLP-1) receptor binding motif for action on a GLP-1 receptor and at least one oligomer conjugation site for binding with at least one oligomer, wherein the oligomer includes a polyethylene glycol moiety (PEG), and/or alkyl moiety.
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