Kenneth Duke James, JR.,Christopher Patrick Laudeman
申请号：
US13392152
公开号：
US20120190613A1
申请日:
2010.08.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention features echinocandin class compounds that have been modified to (i) have activity against one or more fungal species or genera (ii) have increased aqueous solubility (iii) have an increased therapeutic index (iv) be suitable for topical administration and/or (v) be suitable for oral administration. The echinocandin class compounds of the invention include, for example, a PEG, alkyl-PEG, aryl-PEG, alkaryl-PEG, PEG-alkyl, PEG-aryl, or PEG-alkaryl substituent.
