A monoclonal antibody to CD44 for use in the treatment of head and neck squamous cell carcinoma

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专利权人:

F. Hoffmann-La Roche AG;University of Miami

发明人:

Da Cruz, Luis A.G.,Franzmann, Elizabeth Jane

申请号：

AU2011212485

公开号：

AU2011212485B2

申请日:

2011.02.02

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

A monoclonal anti-CD44 antibody, or antigen-binding fragment thereof, for use in the treatment of a head and neck squamous cell carcinoma (HNSCC) in a mammal, wherein said HNSCC is characterized by the expression of CD44. Said monoclonal antibody may be produced by the hybridoma deposited with the ATCC with the accession number PTA-4621, and may be chimeric or humanized versions thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/