A MONOCLONAL ANTIBODY TO CD44 FOR USE IN THE TREATMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA

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专利权人:

F. HOFFMANN-LA ROCHE AG;UNIVERSITY OF MIAMI

发明人:

DA CRUZ, LUIS A.G.,FRANZMANN, ELIZABETH, JANE

申请号：

SG2012054847

公开号：

SG182704A1

申请日:

2011.02.02

申请国别(地区):

SG

年份:

2012

代理人:

摘要：

A monoclonal anti-CD44 antibody, or antigen-binding fragment thereof, for use in the treatment of a head and neck squamous cell carcinoma (HNSCC) in a mammal, wherein said HNSCC is characterized by the expression of CD44. Said monoclonal antibody may be produced by the hybridoma deposited with the ATCC with the accession number PTA-4621, and may be chimeric or humanized versions thereof.

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中国工程科技知识中心

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http://www.ckcest.cn/home/