MATRIX METALLOPROTEINASE-9 HEMOPEXIN DOMAIN INHIBITORS AND METHODS OF TREATMENT USING SAME

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专利权人:

The Research Foundation for The State University of New York

发明人:

Iwao OJIMA,Vincent ALFORD,Anushree KAMATH,Jian CAO,Xiadong REN,Nicole SAMPSON,Monaf AWWA

申请号：

US16494984

公开号：

US20200017452A1

申请日:

2018.03.22

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Small molecule inhibitors are claimed that selectively target the hemopexin domain of matrix metalloproteinase 9 (MMP-9) and do not inhibit the protease's catalytic functions. A method of treating cancer in a patient in need thereof with the compounds of the invention is also claimed.

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