The present invention relates to a composition for promoting erythroid cell differentiation or proliferation containing a monoacetyldiacylglycerol compound as an active ingredient, a pharmaceutical composition for preventing, treating or improving erythropenia containing the composition, and a health functional food composition. Since the monoacetyldiacylglycerol compound of the present invention has an excellent differentiation or proliferation promoting effect on erythroid cells, it overcomes the side effects of currently used anemia treatment agents, and is effective in treating erythrocytopenia as a compound having no toxicity but excellent therapeutic effect. It is usefully used in a composition for prevention, treatment and improvement.本発明はモノアセチルジアシルグリセロール化合物を有効成分として含有する赤血球系細胞分化又は増殖促進用組成物及びこれを含む赤血球減少症の予防、治療又は改善用薬学的組成物、健康機能食品組成物に関する。本発明のモノアセチルジアシルグリセロール化合物は赤血球系細胞の分化又は増殖促進効果が優秀なので、現在使用される貧血治療剤の副作用を克服し、毒性がないながら治療効果が優秀な化合物として赤血球減少症の予防、治療及び改善用組成物に有用に用いられる。